About
HitChem supplies screening libraries used to discover hit compounds in the early stages of drug development. It offers Diversity, CNS, CRBN Molecular Glue, Covalent and Cyclic Peptide libraries that are ready to use for HTS (high-throughput screening), as solutions in 384-well plates and as powders. B2BIO will guide you in choosing a library that fits your research direction, such as small molecules, targeted protein degradation (TPD), covalent inhibitors or peptides, and provide a quote.
Products
Product Lines
Diversity Library
- 53,359 small molecules selected by drug-likeness criteria (in stock)
- General-purpose library for HTS on novel targets and hit discovery
- 384-well DMSO solution · powder (Cherry Pick available)
CNS Library (SP3 Enriched)
- 14,000 small molecules with a high fraction of SP3 carbons and few rotatable bonds (in stock)
- For hit discovery on CNS targets
- 384-well DMSO solution · powder
CRBN Molecular Glue Library
- Designed around validated CRBN binders and novel binders discovered in-house
- For molecular glue and targeted protein degradation (TPD) research
- 384-well solution · powder
Covalent Library
- Acrylamide 6,383 · Alkynamide 3,948 · Vinyl Sulfonamide 3,948 compounds (cysteine-targeting)
- Phenyl Carbamate 3,948 compounds (serine-targeting)
- 384-well DMSO solution · powder
Cyclic Peptide Library
- Cyclic peptides designed with a proprietary algorithm that increases sequence and physicochemical diversity
- Uses non-natural amino acid monomers (per the manufacturer's flyer)
- 384-well solution · powder
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