About
A company specializing in chromatography packing materials and columns, founded in Kyoto, Japan, in 1980. Its purification solutions extend from analytical to production scale, including BioPro IEX resins and the SmartSep series for antibody and nucleic acid purification, ECO and ECOPLUS glass columns for the laboratory, DAC columns for production, and ChromaCon continuous chromatography. YMC Korea (Pangyo), founded in 2011, provides technical support in Korea.
Products
Product Lines
Resins for Biopurification
- BioPro IEX Q75 · S75 (capture) · BioPro SmartSep Q/S 30·20·10 µm (polishing)
- MacroSep IEX Q (AAV · plasmid) · BioPro HIC
- YMC-SEC MAB · YMC-Pack Diol (SEC)
- YMC-Triart Bio C4 · C18 (300 Å) · YMC-Triart Prep packing materials
Columns
- ECO glass columns (low to medium pressure, from 1 cm diameter) · ECOPLUS (30–80 bar) · PilotPLUS
- DAC production columns · Prep HPLC columns (YMC-Actus)
Systems
- Contichrom CUBE · TWIN continuous chromatography (ChromaCon)
- EcoPrime purification systems (YMC Process Technologies)
How to choose
Product Selection Information
Main Uses
- Ion exchange chromatography capture step (Q75 · S75)
- Intermediate purification · polishing steps (SmartSep Q/S)
Selection Criteria
- Exchanger (Q or S) suited to the target molecule's isoelectric point and the operating pH
- Process step: capture or intermediate purification · polishing
- Particle size: balance between resolution and operating pressure
- Column scale and resin volume needed
- Technical documents to request: regulatory support file · cleaning conditions
Confirmed Specifications & Options
- For capture: BioPro IEX Q75 · S75 (75 µm)
- For polishing: BioPro IEX SmartSep Q/S 10 · 20 · 30 µm
- Pack sizes: 50 mL ~ 20 L (manufacturer's data)
- Regulatory Support File: provided after an NDA is signed (manufacturer's data)
What to Tell Us
- Target molecule and its isoelectric point · molecular weight
- Process step and sample composition (conductivity · pH)
- Resin and operating conditions currently in use
- Column size and resin volume needed
- Regulatory support documents needed
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