B2BIO.co.kr ↗
English
한국어English中文日本語Español
Request a Quote
Home › Solutions › Purification & Chromatography

Purification & Chromatography

Purification & Chromatography

Downstream

Purification & Chromatography

Downstream purification determines both the quality and the cost of biopharmaceuticals. We cover the entire scale-up path: Protein A, IEX, HIC and SEC resins; laboratory glass columns through to automated production columns; lab, pilot and process purification systems; TFF and biopumps; and continuous chromatography.

Product Lines
  • Protein A · IEX · HIC · SEC · mixed-mode resins
  • Lab · pilot · production columns, automated columns
  • Protein purification systems (lab → process)
  • TFF systems · biopumps · buffer preparation
  • Continuous chromatography · Prep HPLC

Brands at This Stage

Inscinstech
Inscinstech Exclusive in Korea
From lab to process: protein purification systems
Purification & Chromatography
RJ Bio
RJ Bio
Downstream purification equipment — automated columns, biopumps, TFF
Purification & Chromatography
Bestchrom
Bestchrom
From Protein A to SEC: production-scale chromatography resins
Purification & Chromatography
YMC
YMC
Resins and columns for biopurification, from Kyoto, 1980
Purification & Chromatography

Product Selection Information

These are the criteria to look at when choosing a product for your application, and the information that is helpful to share when you contact us. Specifications and options list only what has been confirmed.

Protein A Affinity Resins
Bestchrom · Purification & Chromatography

Protein A Affinity Resins

Ask About Protein A Resins
Main Uses
  • Protein A affinity chromatography purification step
  • Packing of laboratory and process columns (prepacked · empty column product lines)
Selection Criteria
  • Target molecule: antibody type and format
  • Dynamic binding capacity and residence time conditions
  • Cleaning (CIP) conditions and alkaline stability
  • Process scale · column size · operating pressure
  • Technical documents to request: lifetime validation · ligand leakage data
Confirmed Specifications & Options
  • AT Protein A Diamond · Diamond Plus · Diamond Ultra
  • Prepacked columns · empty process column product lines
What to Tell Us
  • Target molecule and production cell line
  • Culture titer and batch volume
  • Protein A resin and operating conditions currently in use
  • Column size and target number of cycles
  • Regulatory and validation documents needed
Guide · What to Look at When Comparing Protein A Resins
Ion Exchange Resins (BioPro IEX)
YMC · Purification & Chromatography

Ion Exchange Resins (BioPro IEX)

Ask About Ion Exchange Resins
Main Uses
  • Ion exchange chromatography capture step (Q75 · S75)
  • Intermediate purification · polishing steps (SmartSep Q/S)
Selection Criteria
  • Exchanger (Q or S) suited to the target molecule's isoelectric point and the operating pH
  • Process step: capture or intermediate purification · polishing
  • Particle size: balance between resolution and operating pressure
  • Column scale and resin volume needed
  • Technical documents to request: regulatory support file · cleaning conditions
Confirmed Specifications & Options
  • For capture: BioPro IEX Q75 · S75 (75 µm)
  • For polishing: BioPro IEX SmartSep Q/S 10 · 20 · 30 µm
  • Pack sizes: 50 mL ~ 20 L (manufacturer's data)
  • Regulatory Support File: provided after an NDA is signed (manufacturer's data)
What to Tell Us
  • Target molecule and its isoelectric point · molecular weight
  • Process step and sample composition (conductivity · pH)
  • Resin and operating conditions currently in use
  • Column size and resin volume needed
  • Regulatory support documents needed
Inscinstech

Inscinstech

From lab to process: protein purification systems

Brand DetailsContact
Protein Purification Systems
  • Unique AutopreS — single-pump lab scale (small sample volumes · condition screening)
  • Unique AutoPure — FPLC for research · process development
  • Unique AutoPure Plus · Pilot 600 · Process — for pilot · production
  • Fraction collectors (enclosed · temperature-controlled)
Synthesis · Assembly · Filtration
  • Unique AutoOligo® large-scale nucleic acid (oligo) synthesizer
  • Unique AutoTFF automated TFF system
  • Unique AutoMCD nanoplasmid · nanoparticle assembly system
Other
  • Bioreactors (glass · stainless steel · single-use)
  • Preparative HPLC · capillary electrophoresis ISCE-1000
  • Unique CDSystem chromatography workstation (supports 21 CFR Part 11 · GLP · GMP requirements)
RJ Bio

RJ Bio

Downstream purification equipment — automated columns, biopumps, TFF

Brand DetailsContact
Chromatography Columns
  • i-Axi® automated (in-situ) columns
  • Easy Axi manual columns
  • Agi stirred columns
Pumps · Filtration Systems
  • iBio® intelligent biopump (4-piston diaphragm)
  • Automated · simplified · single-use flow path TFF systems
  • Depth filtration systems
Chromatography · Process Systems
  • Automated · simplified · single-use flow path chromatography systems
  • iBio® buffer preparation system · inline dilution
  • Alkaline lysis systems · custom systems
Bestchrom

Bestchrom

From Protein A to SEC: production-scale chromatography resins

Brand DetailsContact
Affinity
  • AT Protein A Diamond · Diamond Plus · Diamond Ultra (alkali-stable recombinant Protein A)
  • Extrem A Diamond · Novo-A Diamond
  • Diamond Protein L · IgM Cap Mustang
Ion Exchange · Mixed-Mode
  • BestPoly 30Q · 15Q, Diamond Q Mustang · Mustang XL, Q Bestarose BB
  • Diamond MMC · MMC Mustang · MIX-A · MIX-A Mustang, MMC Bestarose FF
HIC · SEC · Other
  • Diamond Phenyl (HS/LS) · Phenyl Bestarose HP · FF
  • Chromdex S-100 · 30PG/75PG/200PG, Bestarose 4FF · 6FF · CL-4B · CL-6B
  • NHS-activated Bestarose 4FF (pre-activated), BestPoly 30RPC · 15RPC (reversed phase)
  • Prepacked columns · empty process columns · microcarriers for cell culture
YMC

YMC

Resins and columns for biopurification, from Kyoto, 1980

Brand DetailsContact
Resins for Biopurification
  • BioPro IEX Q75 · S75 (capture) · BioPro SmartSep Q/S 30·20·10 µm (polishing)
  • MacroSep IEX Q (AAV · plasmid) · BioPro HIC
  • YMC-SEC MAB · YMC-Pack Diol (SEC)
  • YMC-Triart Bio C4 · C18 (300 Å) · YMC-Triart Prep packing materials
Columns
  • ECO glass columns (low to medium pressure, from 1 cm diameter) · ECOPLUS (30–80 bar) · PilotPLUS
  • DAC production columns · Prep HPLC columns (YMC-Actus)
Systems
  • Contichrom CUBE · TWIN continuous chromatography (ChromaCon)
  • EcoPrime purification systems (YMC Process Technologies)

Guides for This Stage

All Guides
Purification & Chromatography · Last reviewed 2026.10.09

What to Look at When Comparing Protein A Resins

Protein A resins cannot be compared on price per liter or catalog binding capacity figures alone. You need to look together at binding capacity measured at the same residence time and breakthrough criterion, cleaning resistance and lifetime, impurity removal, cost per g of antibody, and regulatory documentation.

Read ›

Request a Quote · Purification & Chromatography

Tell us your process stage and the product lines you need, and our technical specialists will respond quickly. TEL +82-2-6409-9338 · info@b2bio.co.kr

Contact Us
↑